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Post-Doc Position | University of Bordeaux | France

Posted by kaury.balcom | April 12, 2022
University of Bordeaux Post-Doc Position

Starting Date: july 2022<
Duration: 24 (+12) months Location: INRAE Bordeaux / Universit  de Bordeaux
Proportion of work: full-time
Salary: 31k€ yearly before-tax salary (approx. 25k€ net)
Desired level of education: PhD
Experience required: PhD with or without post-doctoral research experience

A 2 years (+1) position supported by Bordeaux Plant Science (BPS) research program is available in the UMR EGFV (Ecophysiology and Functional Genomics of the Grapevine)in Bordeaux, France.

Job description: A distinctive feature of grapevine is that its economical value derives more from the quality of its fruits than its absolute yield. Berry quality is a complex trait linked to its composition (its oenological potential), which results from asynchronous accumulation of primary (hexoses, organic acids, amino-acids) and secondary (polyphenols, aroma and aroma precursors) metabolites during fruit growth and ripening. It is under the dual control of the genotypes (rootstock, scion), the epigenome (epigenetic marks, small RNAs, viruses) and of the environmental factors, one of the most prominent being temperature, which affects berry yield, phenology and metabolism. Thus, studying the (epi)genetic determinants and the physiological mechanisms underlying berry quality buildup during ripening and the trade-offs between fruit yield and quality is a challenge of uttermost importance for grapevine and wine research community, with the view of using them as levers for future grape breeding programs.

In this context, one the main goals of the VIN-WIN project is to analyze the contribution of the various sources of grapevine genetic diversity (genotypes of both scion and rootstock) to the plasticity of the fruit yield versus berry and wine composition balance. To this end, several grapevine populations will be analyzed.

The post-doctoral project will focus on the characterization of a Vitis vinifera cv. S millon clonal population of 59 genotypes, at the genomic, epigenomic, virome, metabolomic and phenotypic levels, in relationship with berry composition at harvest and wine quality. The successful applicant will

implement next-generation genomic sequencing, genome assembly and re-sequencing, SNP and InDel detections, as well as DNA methylation and RNA-seq approaches. He/she will also participate in field phenotypic notations and berry composition analysis. He/she will benefit of the support of the bioinformatics group of UMR EGFV and of the metabolomics platform of UMR BFP laboratories.

Main activities:

1. Exploring the genomic diversity in the S millon grapevine clonal population by producing a high quality reference genome and a genotyping-by-sequencing analysis of the 59 accessions of the population;

2. Analyzing the epigenome, transcriptome and virome of a selected subset of the clonal population;

3. Participating in the population field phenotyping (clone phenology, vigor, yield and ripening dynamics) ;

4. Participating in berry composition analysis;

5. Building correlations networks between virome composition, epigenetic regulation, genomic variations, berry and wine metabolomes in order to assess their relative contribution to fruit and wine composition variations.

Environment: The candidate will be hosted at the UMR 1287 EGFV (Ecophysiology and Functional Genomics of the Grapevine) laboratory, located at the Institut des Sciences de la Vigne et du Vin (ISVV) at the INRAE campus of Villenave D’Ornon, France. He/she will have strong interactions with the UMRs 1332 BFP (Fruit Biology and Pathology) and UMR Oenologie also located at the INRAE campus of Villenave D’Ornon. The INRAE campus constitutesa highly stimulating scientific environment.

Skills: We are looking for highly motivated candidates with a good publication track-record and a strong commitment to research in plant genetics/genomics and bioinformatics. A previous experience in metabolomics would be highly appreciated but is not mandatory, provided that applicants are ready to learn and get involved in such approaches. Good english communication skills (written and oral) are expected.

Selection process: The candidates will submit their application consisting in a motivation letter and a detailed CV (including training background, research experience publication and communication lists), before the 5th of May, 2022, for a starting date anytime around the 1st of July 2022.

Team/lab website:

Selected publications:

�  Arrizabalaga et al. (2018)

�  Arrizabalagaet al. (2020)

�  Candresse et al. (2018)

�  Girollet et al. (2019)


BERT Pierre-Franois(UMR EGFV):